So you're interesting in using Magnesium Citrate?

Maybe you've heard that Magnesium can help with weight loss, or maybe you found out that your serum levels are low. 

Either way it doesn't matter, because the truth is that Magnesium is critical for optimal health and is involved in a  number of metabolic pathways in the body.

The deficiency of this critical nutrient may result in a number of negative symptoms.

That's the bad news.

The good news is that replacing this nutrient isn't very difficult.

Below we are going to go over 9 powerful reasons you should consider using magnesium citrate, back by science of course, including how I use this in my practice for maximum benefit.

Let's dive in...

9 Reasons to Consider Supplementing with Magnesium Citrate

Before we talk about the many benefits of magnesium citrate we need to establish some basics.

First:

We need to understand what magnesium citrate actually is.

Magnesium is the critical nutrient and citrate is the portion that magnesium is bound to. 

Magnesium can be bound to different compounds to either increase absorption, decrease absorption, or alter how magnesium gets into your cells.

Magnesium citrate is special because much of how it is absorbed.

Much of the magnesium bound to citrate remains in the gastrointestinal tract which has special implications on GI function. 

Because magnesium can act on smooth muscle it can improve the regularity of bowel movements (making it a potent treatment for constipation).

But let's be clear:

The benefits of Magnesium citrate come from the magnesium portion (the same is true of other forms of magnesium), so realistically you can still get much of the benefits that magnesium citrate providers while using other forms of magnesium.

Except magnesium bound to oxide. Don't use this low quality form of magnesium!

Below I've attached a magnesium formulations with different binding components: 

Magnesium citrate table

How to Properly Supplement with Magnesium

So how should you use magnesium for the maximum benefit?

When we talk about replacing any nutrient we are most concerned with the quality of the supplement but also the dosing.

If you take a low quality supplement (as in the case of magnesium oxide) you won't get the maximum absorption and thus your benefit will be limited.

Likewise if you use a dose that isn't high enough you will not experience the benefits I am discussing here in this article. 

When it comes to magnesium citrate there are some general guidelines you should follow:

  • Base dose on your symptoms (not on your serum levels)
  • Dosages of up to 2,000mg daily may be required
  • Titrate dose based on your bowel movements (increase your dose to cause loose bowel movements but never diarrhea)
  • High dosages may be required for up to 6 months to replete cellular levels of magnesium (note that serum levels of magnesium do not accurately reflect intracellular levels)
  • Certain hormone imbalances  cause changes in the kidneys which influence serum and cellular magnesium levels, dosing should be adjusted for these conditions
  • Magnesium is best taken at night because it can provide a calming effect to the brain and body
  • Avoid taking magnesium with other oral medications (especially thyroid hormone)
  • Patients with poor diets may need to supplement for longer and more sustained periods of time

Use these as guidelines when supplementing with magnesium and remember that it may take several weeks (up to 4-6 weeks) before you notice an improvement. 

This supplement is a combination of both potency and purity and does not include any extra fillers, dyes or binders.

Now that we understand how to supplement with Magnesium citrate let's jump into the many benefits this nutrient might provide:

#1. Magnesium Helps with Weight Loss

I've written about this extensively in this post, but it's worth going over a few important point here. 

Magnesium citrate may help with weight loss through a number of mechanisms:

First:

Magnesium itself has a positive influence on insulin signaling and may help in reversing insulin resistance.

Given that up to 50% of the US population has either pre diabetes or diabetes (both conditions of insulin resistance), there is a good chance you fall into this category. 

That means taking magnesium may help improve your insulin levels and ultimately lead to a state where weight loss is more easily achieved.

Second:

Magnesium citrate may help to increase cellular energy levels and ATP production via mitochondrial pathways. 

Studies have shown that adding magnesium may improve energy production during exercise resulting in longer and more sustained caloric burn. 

This change in energy production may be responsible for a reduction in symptoms of fatigue and indirectly lead to increased activity levels.

Higher energy production = higher resting energy expenditure = more calories burned at rest

This benefit assumes that the person supplementing is deficient in magnesium, however. 

So taking magnesium if you have sufficient cellular and serum levels may not help with weight loss in this population. 

Third:

Magnesium citrate helps to reduce total body water and stool through its laxative like effects on the GI tract. 

This improvement in regularity may also bring upon changes in your microbiome and microbiota which may have a positive effect on energy balance as well.

Remember though that this benefit does not necessarily provide a reduction in total fat mass, which is what people want when they are looking for weight loss. 

The temporary loss in water weight may move the scale, but may not do much for the reduction in fat in your body.

The combination of these benefits probably all contribute to weight loss that is seen in some patients who supplement with Magnesium citrate.

Remember, for the best results it's necessary to combine magnesium supplementation with other lifestyle changes including diet, exercise and stress reduction.

#2. Magnesium Improves the Quality of your Sleep and Helps Treat Insomnia

Magnesium supplementation has been shown in many studies to help improve both the depth and quality of sleep. 

This is important for several reasons:

A general lack of sleep has been associated with multiple medical conditions including an increased risk of developing diabetes, a reduction in immune system function and an increased levels of inflammatory markers. 

Yikes.

A lack of sleep is described as less than 8 hours of restful and high quality sleep each night. 

How many of you fall into that category? Not many I'm sure.

What's important is that Magnesium can help increase the depth of your sleep and actually reduce your risk of these conditions.

This may be yet another reason why magnesium citrate may help with weight loss because a general lack of sleep is also associated with weight gain. 

You can use magnesium to help improve your sleep by taking it 30-60 minutes prior to bed time.

Use doses of at least 300-400mg at night for the full effect.

In my experience patients who tend to get an improvement in sleeping habits with the use of magnesium tend to have an "over-active" mind, or a mind that they can't "shut off" at night.

Having said that many patients still notice improvements with magnesium supplementation.

#3. Magnesium helps Treat Constipation

As was mentioned previously one of the most well known benefits of using magnesium citrate is its ability to help improve bowel movement regularity.

The citrate components helps magnesium stay in the bowels longer, helps relax smooth muscles and helps move stool through the GI tract.

To get this benefit with magnesium citrate you may need to use dosages as high as 2,000mg per day. 

To start supplementation simply start with 200-300mg taken at night (30-60 minutes prior to bed time) and increase your dose by 100-200mg per night until you have loose stools in the morning.

If you develop diarrhea during this process then you should back down on the dose.

While magnesium citrate will most definitely help you with bowel movements it's best to focus on the CAUSE of your constipation. 

Magnesium citrate acts as a way to increase bowel movements but doesn't necessarily treat the underlying cause of your constipation and may just mask the symptom.

Having said that it is important to have consistent bowel movements because stool helps eliminate potentially harmful bacteria and other breakdown products in your body. 

#4. Magnesium Helps Calm the Mind and May Reduce Symptoms of Anxiety & Depression

Magnesium deficiency has been associated with depressive symptoms.

What's interesting is that this connection seems at least in part to be due to the changes in the microbiome  due to magnesium depleted foods. 

Magnesium supplementation can be used as an adjunct to other treatments for depression. 

That means you can add magnesium to anti-depressants and other medications to get this benefit. 

Low magnesium has also been associated with changes to the HPA axis which may result in symptoms of anxiety. 

The addition of magnesium can help to "calm down" the mind, reduce symptoms of anxiety and help combat depression.

For optimal results using magnesium bound to threonate  might even be more powerful than using magnesium bound to citrate. 

#5. Magnesium can Help Treat Chronic Migraines

Do you suffer from headaches or even migraines?

Did you know that taking magnesium every day can actually help PREVENT migraines?

Studies show that taking magnesium can actually act as prophylaxis against migraines (without aura).

How this works is not entirely understood but probably has to do with multiple factors:

Believe it or not Doctors still aren't exactly sure what causes migraines (we think it has to do with vascular changes in the arteries/veins).

With that in mind it is felt that magnesium can help relax the smooth muscle which controls the diameter of the arteries and veins which may reduce the frequency that patients experience migraine headaches. 

The moral of the story here is that if you suffer from migraine headaches (without aura) using magnesium supplementation may help to reduce the total number of migraines you experience. 

Note that in order to prevent migraines magnesium should be taken every day regardless of serum levels. 

#6. Magnesium May Help Increase Energy Levels

We touched on this previously but because magnesium is involved in mitochondrial pathways, a deficiency in magnesium may result in the subjective symptom of fatigue or low energy.

Your mitochondria produce energy for your entire body in the form of ATP.

The production of ATP occurs (mostly) in the mitochondrial and requires certain cofactors, enzymes and nutrients for optimal production.

A deficiency in critical enzymes may reduce energy production slightly, and this reduction in energy production is what is subjectively felt as fatigue.

Of course other factors may influence energy levels, but if you are suffering from fatigue AND you have low serum levels of magnesium then supplementing with magnesium may ultimately help to improve your energy levels.

Again, supplementing for low energy may depend on a combination of serum magnesium levels and for the best benefits magnesium should be taken daily.

#7. Magnesium Helps Reverse Insulin Resistance

We touched on this earlier in how magnesium citrate supplementation can help with weight loss section, but it's worth expanding on here...

Magnesium helps your body become sensitive to insulin. 

If you recall the role of insulin is to help push blood glucose (sugar) into your cells.

High levels of insulin shove glucose into your cells (including fat cells) causing insulin resistance at the receptor level.

High levels of insulin cause weight gain due to the growth of fat cells and result in an increased risk of multiple medical conditions including cardiovascular disease.

What you may not realize is just how common the condition of insulin resistance actually is. 

The number of patients with insulin resistance continues to grow and with it the risks and complications of the disease do as well. 

If you have known issues with blood sugar, diabetes or pre diabetes then you have insulin resistance.

If you do I would recommend reading through this article and considering the use of multiple supplements and dietary changes to help influence your insulin sensitivity.

Of these supplements that help reduce insulin resistance, magnesium is front and center.

#8. Magnesium Helps Reduce Muscle Cramps, Twitches and Muscle Aches

Have you ever experienced a Charley horse?

A Charley horse is a painful muscle spasm (usually in the lower legs) that usually doesn't subside until it is stretched out (another painful endeavor). 

These muscle spasms can be triggered by low levels of magnesium.

In addition to these muscle spasms magnesium can help reduce muscle twitches (I'm talking about those pesky eye twitches) and other muscle aches and pains. 

If you are experiencing muscle cramps, aches or pains then supplementing with magnesium citrate may help to reduce these symptoms. 

A word of caution:

Diarrhea can actually induce magnesium deficiency, so high doses of magnesium citrate may be counter productive if your magnesium deficiency and muscle cramps are caused by loose stools.

#9. Magnesium may Help Lower Blood Pressure

Several studies have shown that taking magnesium can actually help to reduce blood pressure levels and act as anti-hypertensive. 

This is felt to be mediated through a combination of factors:

First magnesium helps to relax smooth muscles. As the diameter of your arteries increases blood pressure will necessarily fall. 

In addition magnesium helps to increase nitric oxide levels which has the same effect. 

In addition magnesium acts as a natural calcium channel blocker to reduce the force of contraction of the heart. 

If you have hypertension you may know that many anti hypertensives actually target the calcium channel as well.

The thing to realize about magnesium supplementation for hypertension is that it may not work for everyone. 

However, it is easy enough to add magnesium to your regimen and then monitor your blood pressure levels.

I would not, however, recommend that you go off of your anti-hypertensives in favor of using magnesium without consulting your physician.

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